Helmholtz Institute

Recent events

Featured article in Cell by Terburg et al.

Terburg, Scheggia, del Rio, Klumpers, Ciobanu, Morgan, Montoya, Bos, Giobellina, van den Burg, de Gelder, Stein, Stoop and van Honk have published in article in Cell called ‘The Basolateral Amygdala Is Essential for Rapid Escape: A Human and Rodent Study’. The main points that have been put forward are that the human bilateral BLA damage and silencing in rats result in maladaptive passive fear; that if active escape is feasible, the BLA prevents passive freezing responses via the CeA; that BLA action on an inhibitory CeA pathway permits the adaptive shift to active escape; and that activation of CeA neurons by oxytocin rescues deficient escape in BLA-silenced rats.
The article can be found via: https://www.cell.com/cell/fulltext/S0092-8674(18)31240-6